Arrowhead Pharmaceuticals Hosts R&D Day on Emerging Pipeline of RNAi Therapeutics
PASADENA, Calif.--(BUSINESS WIRE)-- Arrowhead Pharmaceuticals, Inc. (ARWR) is hosting a Research & Development (R&D) Day today in New York to discuss its emerging pipeline of RNAi therapeutics that leverage its proprietary Targeted RNAi Molecule Platform (TRiM™) platform. The event will feature presentations by Arrowhead's management team and Ira Goldberg, M.D., the Clarissa and Edgar Bronfman, Jr. Professor of Endocrinology, and the Director of the Division of Endocrinology, Diabetes, and Metabolism at NYU Langone Medical Center.
Presentations will begin at 8:30 a.m. EDT. A live and archived webcast of the event may be accessed on the Events and Presentations page under the Investors section of the Arrowhead website.
Chris Anzalone, Ph.D., president and chief executive officer of Arrowhead Pharmaceuticals, said: “During the R&D Day, we will discuss our product development strategy as we continue to expand our pipeline and detail the guiding principles that make our R&D organization best-in-class for execution and speed. The clinical data generated to date for multiple drug candidates that leverage our proprietary TRiM™ platform with 432 total doses administered to 214 patients have been very promising. In fact, they have met and, in many areas, exceeded our expectations with respect to tolerability and pharmacologic activity against their respective targets. We now have five candidates in clinical trials, three of which are wholly owned. By the end of 2020, we expect to have at least seven wholly owned candidates in clinical studies, including three in Phase 3 pivotal studies, as well as two partnered programs in Phase 2 studies or later, and drug candidates in four different cell types. We expect to be the first RNAi company in these extra-hepatic cell types. In addition, we continue to make advances to the TRiM™ system, and we are presenting data today demonstrating that a new dimer structure that delivers multiple siRNA sequences together can achieve high levels of knockdown of two different genes simultaneously. These important advances dramatically increase the number of potential diseases that we may be able to address over the coming years.”