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Octoplus september

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had ik maar
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Blijkbaar is er van voor 2009 geen finc. date meer voorhanden op de vernieuwde Octplus website. Mogelijk komt dit nog, maar voor de zekerheid nog even de contractvoorwaarden waaronder Locteron aan Biolex is verkocht. (ik had dit niet op mijn PC maar via via toch teruggevonden;-) )

OctoPlus announces exclusive license and manufacturing agreement for Locteron with Biolex allowing for revenues in excess of 100 million euro
06.10.2008, Leiden, the Netherlands

This agreement will immediately transform OctoPlus into a cashflow positive company

OctoPlus N.V. (“OctoPlus” or the “Company”) (Euronext: OCTO), the drug delivery company, announces today that it has signed an exclusive license and product acquisition agreement to license its share of the commercial rights to its lead product Locteron® to co-development partner Biolex Therapeutics. OctoPlus will remain a partner in the process development and manufacture of Locteron, but without having to make the investments for the upcoming late-stage clinical program. The proceeds of the agreement include among others upfront and milestone payments that amount to a total of US$ 149 million (€ 108 million) in the coming years, and royalties on future Locteron sales. The upfront fee and short-term milestone payments comprise the first significant revenues that OctoPlus generates from the commercialisation of its drug delivery technology PolyActive®. In addition to the cash payments under the agreement, OctoPlus will receive an equity stake in Biolex of up to 3.0%.

License and manufacturing agreement
A co-development agreement for Locteron has been in place between OctoPlus and Biolex since 2005. Highly promising clinical trial results have been published during the collaboration so far and the product is now being evaluated in a US Phase IIa study. Under the terms of the agreement announced today, Biolex will be responsible for the overall development and commercialisation of Locteron. OctoPlus will continue to perform process development and will manufacture Locteron, but will now be paid for these activities.

In summary, OctoPlus will receive:
- An upfront fee of US$ 11 million (€ 8.0 million)
- Milestone payments totaling US$ 138 million (€ 100 million)
- An equity stake in Biolex of up to 3.0%
- Royalties on net product sales. Moreover, OctoPlus retains commercial manufacturing rights to Locteron. The combined revenue from royalties and sale of manufactured product to Biolex will be equivalent to a low double-digit royalty.

Simon Sturge, CEO of OctoPlus*, comments: “We are very excited to have established this license agreement for Locteron with Biolex. This deal is beneficial for OctoPlus in two ways:
- Firstly, we will continue to be involved in the development of a potential blockbuster, but without having to make the expenditures of late-stage clinical development, and
- Secondly the upfront fee, funding of process development and manufacturing activities and milestone payments will transform us into a company with a positive operational cashflow.
This agreement concludes our financing activities and enables us to maintain our focus on being a world-class drug delivery company, using our technologies for the development of our own products and for our partners.”

*On September 16 OctoPlus announced the nomination by the Board of Supervisory Directors of Mr. Sturge as proposed CEO. His appointment will be made official at the Company’s Annual General Meeting of Shareholders, which will be scheduled shortly.

Financing OctoPlus
With this agreement OctoPlus secures long-term revenues for the Company and reduces its expenditure. In addition, the upfront and milestone payments transform OctoPlus instantly into a business with a positive operational cashflow for the foreseeable future. With the completion of this agreement, the Company is now in a position to publish its Annual Report 2007, for which a publication date will be announced shortly.

Conference call and webcast presentation
OctoPlus will hold a conference call and webcast presentation today at 10:00 AM CET. This event can also be followed live via OctoPlus’ website www.octoplus.nl. If you would like to participate in the conference call, please dial in on telephone number +31 (0) 45 631 6902. After the presentation, Simon Sturge, CEO of OctoPlus, will be available to answer questions. After the event, the webcast will be available for replay on the Company’s website.

For further information, please contact:
Rianne Roukema, Corporate Communications, telephone number +31 (71) 524 1071 or e-mail IR@octoplus.nl.

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Hoi patient, Peebee & Harrysnel

Ik lees met veel interesse jullie bijdragen op het forum. Heel veel waardering voor jullie inspanningen om Octoplus te duiden. (natuurlijk ook aan de anderen maar jullie 3-en springen er wel uit) Chapeau & ga aub vooral zo door!

groet, zuurbier
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quote:

patient schreef op 26 september 2012 15:10:

14 en 28 september staat Biolex niet op de rol voor een creditorsmeeting in Durham, vandaar mijn conclusie dat deze op 31 augustus heeft plaats gevonden. Via pacer kan je tegen betaling de stand van zaken mbt bankruptcy cases opvragen. Het blijft openbare info. Ik heb geprobeerd me aan te melden, maar op één of andere manier wordt ik steeds geweigerd. Misschien alleen voor crediteuren en/of amerikanen mogelijk? Octoplus zou die info gewoon kunnen opvragen bij de trustee.

En voor wat betreft Synthon denk ik dat er een één tweetje met Octoplus wordt gespeeld. Met de Lemna produktie techniek in handen van Synthon en het Poly active in handen van Octoplus hebben ze al 2 van de 3 assets om doorontwikkeling van Locteron mogelijk te maken in handen. Nu het eigendomsrecht van Locteron nog. Ook is met de aankoop van het Lemna productie systeem door Synthon voorkomen dat een andere marktpartij (bv Merck Pegintron)zowel het produktiesysteem als het eigendomsrecht verkrijgt voor een prikkie en daarmee Octoplus buitenspel zet.
Volgens mij heeft Synthon dat eigendomsrecht ook al binnen [ achter de schermen ] anders zijn ze dus 4 miljoen kwijt want als een ander Locteron koopt zijn die niet verplicht om Interferon bij Synthon te kopen ze hebben volgens mij alles al geregeld met Biolex en Octoplus want ze geven geen 4 miljoen weg !!
Debit or Credit
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Heb gisteren klein setje octoplus gekoct. Mdxhealth zal als eerst vertrekken. Hou die eens in de gaten!
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In midst of dissolution of Biolex, Locteron could bring some value

Triangle Business Journal by Lauren K. Ohnesorge, Staff Writer
Date: Friday, September 21, 2012, 6:00am EDT

www.bizjournals.com/triangle/search/r...

Lauren K. OhnesorgeStaff Writer- Triangle Business JournalEmail
PITTSBORO – Duckweed is about all that remains of what used to be a $190 million company.

Locteron, a Hepatitis C drug candidate created ----from duckweed-----, was to be the drug that pushed Pittsboro-based Biolex Therapeutics to blockbuster status, but Phase 3 financing never happened.

Now, unless well-backed bidders surface to buy the rights to Locteron, Chapter 7 bankruptcy threatens to be Biolex’s lasting legacy. Biolex listed $38 million liabilities in its bankruptcy filing and only $803,000 in assets.

Locteron still has one cheerleader: Jan Egberts, CEO of Octoplus, a Netherlands-based company that signed a deal with Biolex in 2005 ...
arreno
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