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Sanofi, Sanofi en nog eens Sanofi

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flosz
0
quote:

Rockefeller schreef:

Sanofi-aventis Delivers 2008 Results Above Guidance

2008 performance

- EPS2 growth at constant euro/dollar exchange rates above guidance (up 11.2% against guidance of around 9%)
- Solid sales performance driven by Lantus® (up 27.7%), Taxotere® (up 13.2%), Lovenox® (up 10.6%), Plavix® (up 10.5%), Aprovel® (up 14.2%) and vaccines (up 9.6%)
- Successful launch of Pentacel® and filing for approval of Multaq® and Ciltyri® in the United States and Europe
- Growth ahead of the market in the United States, and double-digit growth in emerging markets and in Japan
- Continued improvement in operating ratios
- Net debt reduced to €1.8 billion
- Proposed dividend of €2.20 per share, payable April 28, 2009

2009 guidance

In 2009, sanofi-aventis expects growth in adjusted EPS excluding selected items1 of at least 7% at constant exchange rates, barring major adverse events such as the launch of a generic of Lovenox® in the United States
Exploring external growth opportunities
Our business development must be perfectly integrated in our overall strategy and translate into disciplined
acquisitions and partnerships to build or strengthen platforms for long-term growth and create value for our
shareholders. We have already taken first steps in this direction through our alliance with Regeneron, our
acquisitions of Acambis plc and Symbion Consumer, and our bid for Zentiva. We are encouraging business
development initiatives within operations in order to reinforce our regional approach. Our external research
collaborations will be broadened so that we further develop creativity within R&D and deliver innovation to
patients. The position of Chief Strategic Officer has been created at the Executive Committee level to achieve
this integrated approach to strategy and business development.

Human Vaccines
Fourth-quarter consolidated net sales for the Human Vaccines business were up 8.9% at €709 million, with fullyear
growth reaching 9.6% at €2,861 million. In the United States, 2008 full-year net sales were up 9.7% at
€1,683 million.
Net sales of influenza vaccines in 2008 rose 1.5% to €736 million. This increase includes the shipment during
the second quarter of a batch of H5N1 vaccine to the U.S. Department of Health and Human Services worth
$192.5 million (vs. $113 million in 2007). Fourth-quarter sales of influenza vaccines in the United States were
down compared to previous year, as three-quarters of 2008 shipments were completed during the third quarter
of the year.
Net sales of Menactra® (quadrivalent meningococcal meningitis vaccine) rose 7.9% in 2008 at €404 million.
Pentacel® -- the first 5-in-1 pediatric combination vaccine to protect against diphtheria, tetanus, pertussis, polio
and haemophilus influenzae type b licensed in the United States-- confirmed its success with strong sales
uptake promptly after its launch in July 2008, reaching net sales of €56 million in the fourth quarter and €82
million in 2008.
Adacel® (adult and adolescent tetanus-diphtheria-pertussis booster) continued to perform very well in the
United States, up 35.6% in the fourth quarter to €54 million and by 20.0% for the year, reaching €255 million.
Sales of Act-Hib® increased by 19.9% reaching €120 million in 2008, driven by the significant commercial and
industrial effort to provide additional doses to the US market during competitor’s supply shortage combined with
Act-Hib® launch in Japan in November 2008.
2008 sales growth was also driven by the uptake of Pentaxim® -- another 5-in-1 pediatric combo vaccine,
which protects against diphtheria, tetanus, pertussis, polio and haemophilus influenzae type b -- in the “other
countries” region.

Phase II
Flu Cell Culture
Influenza Vaccine
New production method
P.27
en.sanofi-aventis.com/binaries/200902...
Uit Crucell's PB: Influenza - Seasonal Flu Vaccine (FluCell collaboration with
sanofi pasteur): This seasonal influenza vaccine is being
developed by Crucell's partner sanofi pasteur, using PER.C6®
technology. Phase II testing of the cell based influenza vaccine
was initiated in the U.S. in November 2007. In the third quarter
of 2008, Crucell received a milestone payment from sanofi pasteur
for progress of the Phase II trials involving healthy adult
volunteers in the U.S. The trials focus on the safety profile and
immunogenicity of the cell-based vaccine.

Paris, France – February 11, 2009 – Sanofi-aventis announced today that Laurence Debroux is
appointed Senior Vice-President, Chief Strategic Officer (CSO).
In light of the implementation of the Group’s development strategy, it has been decided to create the
position of Chief Strategic Officer at the Executive Committee level.
This position will cover all Group’s business development and acquisition activities as well as corporate
planning, financial and economic evaluation of internal and external projects, and strategic intelligence.
The CSO will ensure that development projects are coherent with corporate strategy and fulfill rigorous
requirements for shareholder value creation.
Laurence Debroux is appointed to this position and will report to Chris Viehbacher, Chief Executive
Officer of sanofi-aventis.
Laurence was previously Senior Vice President, Chief Financial Officer. She will keep this position and
ensure an orderly transition pending the imminent appointment of a new CFO.
en.sanofi-aventis.com/binaries/200902...
gogogoo
0
Sanofi-Aventis reveals targets for expansion
By Andrew Jack in London

Published: February 11 2009 00:00 | Last updated: February 11 2009 00:00

The new chief executive of Sanofi-Aventis plans to expand further into consumer health, generics and biological medicines in his efforts to transform the French pharmaceuticals group.

In an interview with the Financial Times, Chris Viehbacher said that he would shift Sanofi-Aventis from “an EU/US-centric pharma company to a global healthcare company” through acquisitions and internal restructuring.

EDITOR’S CHOICE
Sanofi to join Pfizer on acquisition trail - Feb-01New Sanofi chief puts reshuffle into action - Dec-11Pressure on new Sanofi chief - Dec-01Sanofi reaches settlements on generics - Nov-19Sanofi raises forecast after strong quarter - Oct-31Sanofi-Aventis weight loss drug pulled by EU - Oct-23He said that he would respect the company’s “very strong culture” and commitment to provide medicines to the poor, while removing bureaucracy and “making sure we are coming up with healthcare solutions”.

Sanofi-Aventis releases full-year results on Wednesday as investors remain concerned about pressure on the company’s existing drugs and its pipeline of new ones.

Mr Viehbacher said that the company had “missed the boat” on diversifying into biological medicines, and would involve governments and insurers that pay for medical care more in future development to ensure “you bring medicines of value to the marketplace”.

He expressed scepticism about mega-mergers such as Pfizer’s recent $68bn take­over of Wyeth, but said with €4bn ($5.2bn) in yearly free cash flow after dividends, Sanofi-Aventis was well funded to undertake strategic deals.

“On the surface you would have to say the big deals of the past have not necessarily fulfilled the criteria of shareholder value,” he said. ”I don’t want Sanofi-Aventis to be bigger in people and sites. Size is an issue...that led to lower productivity.”

He conceded that more than a fifth of the group’s current sales were threatened by patent expiries by 2012, but stressed that efforts to strengthen its pipeline would be redoubled to address the situation.

He also argued that there would be further ”optimisation of resources”, but the company was “already at the top of the league table” when considering sales, general and administrative costs as a proportion of revenues.

Mr Viehbacher, who previously ran US operations for GlaxoSmithKline but was beaten in the succession race in 2007 to run the UK group, took over Sanofi-Aventis last December after the board ousted Gerard Le Fur.

He praised the legacy of Jean-François Dehecq, the chairman who built Sanofi-Aventis, while adding that “coming from outside means I am bringing a different approach”.
Copyright The Financial Times Limited 2009
www.ft.com/cms/s/0/74ddb35c-f7c6-11dd...

flosz
0
Elias Zerhouni weer gevonden.
****************
Sanofi said it was targeting acquisitions and partnerships, aiming to reinforce its regional approach and its external research collaborations to boost innovation and creativity in research and development.

It said it named Chief Financial Officer Laurence Debroux to the new post of Chief Operating Officer. Debroux will remain finance director, pending the imminent appointment of a successor.
To prop up its R&D, Sanofi said it had begun reviewing its portfolio of drugs and that it had created the posts of Chief Medical Officer, to be taken up by Jean-Pierre Lehner, and Scientific Advisor, which will be taken up by Elias Zerhouni.
uk.reuters.com/article/americasMerger...
_____________________

Uit 2008: Bethesda, MD (Sept. 24)—Elias A. Zerhouni, MD, the director of the National Institutes of Health (NIH), plans to step down at the end of October 2008 to pursue writing projects and explore other professional opportunities. Zerhouni served as NIH director since May 2002.
_________________________

Viehbacher's appointment has buoyed expectations Sanofi will embark on a string of small to medium-sized takeovers, boost cost cuts and restructure its research and development to make up for new drug setbacks and looming loss of patents.
Pfizer (nyse: PFE - news - people )'s planned $68 billion purchase of Wyeth, announced last month, has sparked speculation of a new wave of consolidation in the fragmented pharmaceutical industry.
Viehbacher has already made clear he plans to use the 4 billion euros that Sanofi generates annually in free cash flow to help it grow through acquisitions.
But making a play for its U.S. partner Bristol-Myers Squibb (nyse: BMY - news - people ) , which has a market value of around $45 billion, might be a step too far for Viehbacher so soon after becoming CEO. There has been persistent speculation that Sanofi could buy BMS.
Instead, buying promising small to medium-sized companies -- such as Dutch vaccine maker Crucell which has a market capitalisation of some 1 billion euros -- may be more manageable, according to analysts.
www.forbes.com/feeds/reuters/2009/02/...
[verwijderd]
0
quote:

flosz schreef:

Elias Zerhouni weer gevonden.
****************
Sanofi said it was targeting acquisitions and partnerships, aiming to reinforce its regional approach and its external research collaborations to boost innovation and creativity in research and development.

It said it named Chief Financial Officer Laurence Debroux to the new post of Chief Operating Officer. Debroux will remain finance director, pending the imminent appointment of a successor.
To prop up its R&D, Sanofi said it had begun reviewing its portfolio of drugs and that it had created the posts of Chief Medical Officer, to be taken up by Jean-Pierre Lehner, and Scientific Advisor, which will be taken up by Elias Zerhouni.
uk.reuters.com/article/americasMerger...
_____________________

Uit 2008: Bethesda, MD (Sept. 24)—Elias A. Zerhouni, MD, the director of the National Institutes of Health (NIH), plans to step down at the end of October 2008 to pursue writing projects and explore other professional opportunities. Zerhouni served as NIH director since May 2002.
_________________________

Viehbacher's appointment has buoyed expectations Sanofi will embark on a string of small to medium-sized takeovers, boost cost cuts and restructure its research and development to make up for new drug setbacks and looming loss of patents.
Pfizer (nyse: PFE - news - people )'s planned $68 billion purchase of Wyeth, announced last month, has sparked speculation of a new wave of consolidation in the fragmented pharmaceutical industry.
Viehbacher has already made clear he plans to use the 4 billion euros that Sanofi generates annually in free cash flow to help it grow through acquisitions.
But making a play for its U.S. partner Bristol-Myers Squibb (nyse: BMY - news - people ) , which has a market value of around $45 billion, might be a step too far for Viehbacher so soon after becoming CEO. There has been persistent speculation that Sanofi could buy BMS.
Instead, buying promising small to medium-sized companies -- such as Dutch vaccine maker Crucell which has a market capitalisation of some 1 billion euros -- may be more manageable, according to analysts.
www.forbes.com/feeds/reuters/2009/02/...

Wat een draaikont maar hij komt al aardig richtimg Crucell immers hij had het eerst alleen over small en nu komt medium erbij en 2,5 miljrd is een koopje, toch.
flosz
0
quote:

flosz schreef:

Elias Zerhouni weer gevonden.

Haha handigggggg

Most recently Dr. Zerhouni joined the Bill and Melinda Gates Foundation as a Senior Fellow.
en.sanofi-aventis.com/binaries/200902...
voda
1
Meer winst en omzet voor Sanofi-Aventis
PARIJS (ANP) - De Franse farmaceut Sanofi-Aventis is in het
vierde kwartaal van vorig jaar op een hogere winst en omzet
uitgekomen. De nettowinst steeg met 14 procent naar 1,63 miljard
euro, terwijl de omzet met 2,6 procent toenam tot ruim 7 miljard
euro. Dat maakte Sanofi woensdag bekend.

Topman Chris Viehbacher, die sinds 1 december aan het roer
staat bij Sanofi, liet weten dat hij het bedrijf verder wil laten
groeien door middel van acquisities en samenwerkingsverbanden.
,,Onze ambitie is om een breed ontwikkelde wereldwijde
marktleider te worden in gezondheidszorg,'' aldus Viehbacher.

Sanofi-Aventis is de op twee na grootste
geneesmiddelenproducent ter wereld.

((ANP Redactie Economie, email economie(at)anp.nl, +31 20
504 5999))
[verwijderd]
0
Sanofi-Aventis CEO Seeks Small, Mid-Sized Acquisitions >SNY

Last update: 2/11/2009 2:14:20 AM

PARIS (Dow Jones)--Sanofi-Aventis SA (SNY) plans to pursue small- to mid-sized acquisitions with a focus on emerging markets, generic drugs, non-prescription medicines, as well as prescription drugs, Chief Executive Officer Chris Viehbacher said Wednesday.

In his first outing since his arrival at the helm of the French drugmaker in December, Viehbacher said Sanofi-Aventis is currently reviewing its portfolio of experimental drugs and will report on the findings at the company's first-quarter results.

He added that Sanofi-Aventis could exit whole research and development areas based on the review results.

Viehbacher also said Sanofi-Aventis expects to announce "imminently" the appointment of a new chief financial officer to replace Laurence Debroux, who was appointed chief strategic officer Wednesday.

Company Web site: www.sanofi-aventis.com -By Elena Berton, Dow Jones Newswires; 44 20 7842 9267; elena.berton@dowjones.com (END)

Dow Jones NewswiresFebruary 11, 2009 02:14 ET (07:14 GMT)
[verwijderd]
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quote:

wilb52 schreef:

wie ziet Brus??
Nee ik zie hem hier niet. Hij was ergens in Frankrijk hoorde ik, maar ik wil niet roddelen.....

Haha ja al die berichten en steeds Crucell daarin met een grote rol. Ik schat de kans toch stuk hoger dan 50% in dat die Fransen er met mijn aandeeltjes vandoor gaan.
aossa
0
Sanofi-Aventis Webcast

Gaan inzetten op biologics !

CHMP guidelines on LMWH biosimilars expected in 2009
Potential request for therapeutic equivalence in clinical trial

U.S. regulatory pathway for biosimilars under evaluation
wilb52
0
willemin,Dan heb jij zeker een JAAR abbonnement , om er elke dag naar toe te gaan, voor een bezoek aan het sprookjes bos of carnavalfestival ( rode neuzenfestival )
[verwijderd]
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lees net dat ze die willemn op erikerik.com een IP freeze hebben gegeven, nu hier nog
TraderRon
0
Bent daar geblokt en gaat nu hier om een blok zeuren waarschijnlijk.. Sommige mensen zijn triest.
aossa
0
Sanofi-Aventis webcast

Increase Innovation in R&D

Conduct a detailed objective review of our R&D pipeline

Initial portfolio prioritization resulting in termination of 3 projects

Full review to be completed by end of April 2009 Portfolio Prioritization 1

Partnerships Reallocate resources to external
[verwijderd]
0
we gaan zo de min weer in, het is echt ongelooflijk hoe die koers gedrukt wordt.
ved
0
Niets is uitgesloten, maar de gekozen tijdlijn voor strategische herorientatie maakt een overname door Sanofi op de korte termijn onwaarschijnlijk;
zie pagina 31 v.d. presentatie:

proxy.clients.dbee.com/sanofi/2009021...
[verwijderd]
0
quote:

ved schreef:

Niets is uitgesloten, maar de gekozen tijdlijn voor strategische herorientatie maakt een overname door Sanofi op de korte termijn onwaarschijnlijk;
zie pagina 31 v.d. presentatie:

proxy.clients.dbee.com/sanofi/2009021...
Maar wat ik niet snap is dat, er geen gedrang om de bieding ontstaat, niemand is er bang dat een ander er met de buit er vandoor gaat.
Als Crucell zo hot is dan rammelen ze toch wel aan de deur in rijen van 4!
Niets van dat alles, gewoon ....stilte.
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